Professor Figtree is a Professor in Medicine and Chair of the multi-disciplinary Cardiovascular Initiative at the University of Sydney and an Interventional Cardiologist at the North Shore Cardiac Centre and Royal North Shore Hospital. She is committed to preventing heart attacks through innovations to detect and treat silent coronary artery disease (CAD). She leads a diverse team unravelling key mechanisms underlying susceptibility and response to heart attack, with studies extending from the bench to large cohort studies and clinical trials.

Professor Figtree was former President of the Australian Cardiovascular Alliance which helped secure Federal commitment to the $220 Million MRFF Mission for Cardiovascular Health, which she now Chairs. She is Chair of the Heart Foundation Heart Health Committee, as well as consultant to the NSW OHMR and NSW Health (e.g. on the Expert Advisory Group for Premature Cardiovascular Death). She is co-author on the recent Lancet Commission for Women and Cardiovascular Disease (with initial Lancet publication in April 2021). She is a graduate of the Australian Institute of Company Directors and serves as a non-executive Director on multiple community Boards.